225-226
Editorial Commentary
The elderly—a challenge for appropriate drug treatment
Ulrich Klotz
227-232
Editorial Commentary
Drug-eluting coronary stents: as safe as bare-metal stents, but optimized antiplatelet therapy may further improve clinical outcome
Dietmar Trenk and Franz-Josef Neumann
233-252
Review Article
Clinical use and pharmacological properties of selective COX-2 inhibitors
Shaojun Shi and Ulrich Klotz
253-256
Pharmacogenetics
Distribution of the
GNB3
825C>T polymorphism among Brazilians: impact of population structure
Daniela D. Vargens, Lucas Almendra, Cláudio J. Struchiner and Guilherme Suarez-Kurtz
257-266
Pharmacogenetics
Comparison of SLCO1B1 sequence variability among German, Turkish, and African populations
Jessica Mwinyi, Karla Köpke, Melanie Schaefer, Ivar Roots and Thomas Gerloff
267-273
Pharmacokinetics and Disposition
Pharmacokinetics of eslicarbazepine acetate in patients with moderate hepatic impairment
Luis Almeida, J. Hendrick Potgieter, Joana Maia, M. Alida Potgieter and Fernando Mota, et al.
275-282
Pharmacokinetics and Disposition
Inhibition of metoprolol metabolism and potentiation of its effects by paroxetine in routinely treated patients with acute myocardial infarction (AMI)
Ksenia Goryachkina, Aleksandra Burbello, Svetlana Boldueva, Svetlana Babak and Ulf Bergman, et al.
283-292
Pharmacokinetics and Disposition
Artemisinin and CYP2A6 activity in healthy subjects
Sara Asimus, Trinh Ngoc Hai, Nguyen Van Huong and Michael Ashton
293-301
Pharmacokinetics and Disposition
Examining sex-related differences in enteric itraconazole metabolism in healthy adults using grapefruit juice
Paul O. Gubbins, Bill J. Gurley, David K. Williams, Scott R. Penzak and Scott A. McConnell, et al.
303-309
Pharmacoepidemiology and Prescription
Identification of severe potential drug-drug interactions using an Italian general-practitioner database
L. Magro, A. Conforti, F. Del Zotti, R. Leone and M. L. Iorio, et al.
311-317
Pharmacoepidemiology and Prescription
Prevalence and patterns of methylphenidate use in French children and adolescents
Anne-Laure Knellwolf, Jean Deligne, Flavia Chiarotti, Guy-Robert Auleley and Serena Palmieri, et al.
319-327
Pharmacoepidemiology and Prescription
Rule-based standardised switching of drugs at the interface between primary and tertiary care
Stefanie U. Walk, Thilo Bertsche, Jens Kaltschmidt, Markus G. Pruszydlo and Torsten Hoppe-Tichy, et al.
329-334
Short Communication
Pilot study on the influence of liver blood flow and cardiac output on the clearance of propofol in critically ill patients
Mariska Y. M. Peeters, Leon P. H. J. Aarts, Ferenc A. Boom, Leo J. Bras and Dick Tibboel, et al.