1-2
Editorial
Special issue on cognitive enhancers
T. W. Robbins
3-14
Review
Drug enhancement of memory consolidation: historical perspective and neurobiological implications
James L. McGaugh and Benno Roozendaal
15-36
Review
Pharmaceutical treatment for cognitive deficits in Alzheimer’s disease and other neurodegenerative conditions: exploring new territory using traditional tools and established maps
Raymond T. Bartus and Reginald L. Dean
37-51
Original Investigation
Phospholipase A2 activation as a therapeutic approach for cognitive enhancement in early-stage Alzheimer disease
Evelin L. Schaeffer, Orestes V. Forlenza and Wagner F. Gattaz
53-65
Original Investigation
Methylthioninium chloride reverses cognitive deficits induced by scopolamine: comparison with rivastigmine
Serena Deiana, Charles R. Harrington, Claude M. Wischik and Gernot Riedel
67-78
Original Investigation
The effects of psychotomimetic and putative cognitive-enhancing drugs on the performance of a n-back working memory task in rats
Tracey Ko and John Evenden
79-91
Original Investigation
Galantamine-induced improvements in cognitive function are not related to alterations in α4β2 nicotinic receptors in early Alzheimer’s disease as measured in vivo by 2-[18F]Fluoro-A-85380 PET
J. R. Ellis, P. J. Nathan, V. L. Villemagne, R. S. Mulligan and T. Saunder, et al.
93-102
Original Investigation
Positive effects of nicotine on cognition: the deployment of attention for prospective memory
J. M. Rusted, R. Sawyer, C. Jones, S. L. Trawley and N. L. Marchant
103-109
Original Investigation
Nicotine effects on learning in zebrafish: the role of dopaminergic systems
Donnie Eddins, Ann Petro, Paul Williams, Daniel T. Cerutti and Edward D. Levin
111-123
Original Investigation
Impact of regional 5-HT depletion on the cognitive enhancing effects of a typical 5-ht6 receptor antagonist, Ro 04-6790, in the Novel Object Discrimination task
M. V. King, C. H. Spicer, A. J. Sleight, C. A. Marsden and K. C. F. Fone
125-139
Original Investigation
Increased particulate phosphodiesterase 4 in the prefrontal cortex supports 5-HT4 receptor-induced improvement of object recognition memory in the rat
Guénaëlle Levallet, Maïté Hotte, Michel Boulouard and François Dauphin
141-152
Original Investigation
H3 receptor antagonists reverse delay-dependent deficits in novel object discrimination by enhancing retrieval
Vincent Pascoli, Corinne Boer-Saccomani and Jean-François Hermant
153-163
Original Investigation
Hippocampal SSTR4 somatostatin receptors control the selection of memory strategies
François Gastambide, Cécile Viollet, Gabriel Lepousez, Jacques Epelbaum and Jean-Louis Guillou
165-172
Original Investigation
MK801- and scopolamine-induced amnesias are reversed by an Amazonian herbal locally used as a “brain tonic”
Adriana Lourenço da Silva, Bárbara da Silva Martins, Viviane de Moura Linck, Ana Paula Herrmann and Nathalia Mai, et al.
173-185
Original Investigation
Chronic administration of a Ginkgo biloba leaf extract facilitates acquisition but not performance of a working memory task
Elham Satvat and Paul E. Mallet
187-196
Original Investigation
Intra-amygdaloid infusion of Ginkgo biloba leaf extract (EGb761) facilitates fear-potentiated startle in rats
Yi-Ling Yang, Chia-Wen Hsieh, Yu-Yuan P. Wo, Yi-Chung Yang and Kwok-Tung Lu
197-206
Original Investigation
Memory and psychostimulants: modulation of Pavlovian fear conditioning by amphetamine in C57BL/6 mice
Suzanne C. Wood and Stephan G. Anagnostaras
207-223
Original Investigation
RO4938581, a novel cognitive enhancer acting at GABAA α5 subunit-containing receptors
Theresa M. Ballard, Frédéric Knoflach, Eric Prinssen, Edilio Borroni and Jeffrey A. Vivian, et al.
225-235
Original Investigation
Effects of the AMPA receptor modulator S 18986 on measures of cognition and oxidative stress in aged rats
S. J. Kelly, K. Bernard, C. Muñoz, R. C. Lawrence and J. Thacker, et al.
237-258
Review
A neurocognitive animal model dissociating between acute illness and remission periods of schizophrenia
Martin Sarter, Vicente Martinez and Rouba Kozak
259-273
Review
Recent advances in treating cognitive impairment in schizophrenia
Cherrie Galletly
275-286
Original Investigation
Chronic nicotine improves cognitive performance in a test of attention but does not attenuate cognitive disruption induced by repeated phencyclidine administration
Nurith Amitai and Athina Markou
287-293
Original Investigation
Comparison of haloperidol, risperidone, sertindole, and modafinil to reverse an attentional set-shifting impairment following subchronic PCP administration in the rat—a back translational study
Pascal Goetghebeur and Rebecca Dias
295-306
Original Investigation
Asenapine restores cognitive flexibility in rats with medial prefrontal cortex lesions
David S. Tait, Hugh M. Marston, Mohammed Shahid and Verity J. Brown
307-313
Original Investigation
Remediation of attentional dysfunction in rats with lesions of the medial prefrontal cortex by intra-accumbens administration of the dopamine D2/3 receptor antagonist sulpiride
Marie A. Pezze, Jeffrey W. Dalley and Trevor W. Robbins
315-328
Original Investigation
Aripiprazole ameliorates phencyclidine-induced impairment of recognition memory through dopamine D1 and serotonin 5-HT1A receptors
Taku Nagai, Rina Murai, Kanae Matsui, Hiroyuki Kamei and Yukihiro Noda, et al.
329-341
Original Investigation
Chronic intermittent cold stress and serotonin depletion induce deficits of reversal learning in an attentional set-shifting test in rats
M. Danet S. Lapiz-Bluhm, Alexandra E. Soto-Piña, Julie G. Hensler and David A. Morilak
343-354
Original Investigation
Evaluation of the pro-cognitive effects of the AMPA receptor positive modulator, 5-(1-piperidinylcarbonyl)-2,1,3-benzoxadiazole (CX691), in the rat
M. L. Woolley, K. A. Waters, J. E. Gartlon, L. P. Lacroix and C. Jennings, et al.
355-369
Original Investigation
Mechanisms underlying cognitive enhancement and reversal of cognitive deficits in nonhuman primates by the ampakine CX717
R. E. Hampson, R. A. España, G. A. Rogers, L. J. Porrino and S. A. Deadwyler
371-384
Original Investigation
The glycine transporter 1 inhibitor SSR504734 enhances working memory performance in a continuous delayed alternation task in C57BL/6 mice
Philipp Singer, Joram Feldon and Benjamin K. Yee
385-396
Original Investigation
Procognitive and antipsychotic efficacy of glycine transport 1 inhibitors (GlyT1) in acute and neurodevelopmental models of schizophrenia: latent inhibition studies in the rat
Mark D. Black, Geoffrey B. Varty, Michal Arad, Segev Barak and Amaya De Levie, et al.
397-402
Original Investigation
Facilitation of extinction of operant behaviour in mice by d-cycloserine
David Shaw, Kelly Norwood, Kim Sharp, Lauren Quigley and Stephen F. J. McGovern, et al.
403-409
Original Investigation
The facilitative effects of d-cycloserine on extinction of a cocaine-induced conditioned place preference can be long lasting and resistant to reinstatement
G. Paolone, Fanny Botreau and Jane Stewart
411-417
Original Investigation
Open AccessA placebo-controlled study of sildenafil effects on cognition in schizophrenia
Donald C. Goff, Corinne Cather, Oliver Freudenreich, David C. Henderson and A. Eden Evins, et al.
419-443
Review
Open AccessSelective phosphodiesterase inhibitors: a promising target for cognition enhancement
Olga A. H. Reneerkens, Kris Rutten, Harry W. M. Steinbusch, Arjan Blokland and Jos Prickaerts
445-455
Review
Ameliorating prefrontal cortical dysfunction in mental illness: inhibition of phosphotidyl inositol-protein kinase C signaling
A. F. T. Arnsten
457-476
Review
Lithium and cognitive enhancement: leave it or take it?
Eleftheria Tsaltas, Dimitris Kontis, Vasileios Boulougouris and George N. Papadimitriou
477-485
Original Investigation
Protracted cognitive effects produced by clonidine in Macaca nemestrina performing a delayed matching task
Jerry J. Buccafusco, Scott J. Webster, Alvin V. Terry, Nancy Kille and Donna Blessing
487-495
Original Investigation
Modafinil improves rapid shifts of attention
Natalie L. Marchant, Faddy Kamel, Kezia Echlin, John Grice and Mark Lewis, et al.
497-504
Original Investigation
Effects of atomoxetine and methylphenidate on performance of a lateralized reaction time task in rats
J. David Jentsch, Shawn M. Aarde and Emanuele Seu
505-519
Original Investigation
Open AccessInhibition of the norepinephrine transporter improves behavioral flexibility in rats and monkeys
Emanuele Seu, Andrew Lang, Ronald J. Rivera and J. David Jentsch
521-530
Original Investigation
Tolcapone enhances food-evoked dopamine efflux and executive memory processes mediated by the rat prefrontal cortex
C. C. Lapish, S. Ahn, L. M. Evangelista, K. So and J. K. Seamans, et al.
531-539
Original Investigation
Open AccessMethylphenidate improves response inhibition but not reflection–impulsivity in children with attention deficit hyperactivity disorder (ADHD)
Elise E. DeVito, Andrew D. Blackwell, Luke Clark, Lindsey Kent and Anna Maria Dezsery, et al.
541-547
Original Investigation
When we enhance cognition with Adderall, do we sacrifice creativity? A preliminary study
Martha J. Farah, Caroline Haimm, Geena Sankoorikal and Anjan Chatterjee
549-558
Original Investigation
Glucose administration prior to a divided attention task improves tracking performance but not word recognition: evidence against differential memory enhancement?
Andrew B. Scholey, Sandra I. Sünram-Lea, Joanna Greer, Jade Elliott and David O. Kennedy