107-108
Editorial
Ascent of the kappa-opioid receptor in psychopharmacology
William A. Carlezon and Klaus A. Miczek
109-119
Review
Kappa opioids and the modulation of pain
Bronwyn Kivell and Thomas E. Prisinzano
121-135
Review
The role of the dynorphin–κ opioid system in the reinforcing effects of drugs of abuse
Sunmee Wee and George F. Koob
137-147
Review
Kinase cascades and ligand-directed signaling at the kappa opioid receptor
Michael R. Bruchas and Charles Chavkin
149-159
Original Investigation
Effects of kappa opioids in an assay of pain-depressed intracranial self-stimulation in rats
S. Stevens Negus, Ember M. Morrissey, Marisa Rosenberg, K. Cheng and Kenner C. Rice
161-168
Original Investigation
Consequences of opioid receptor mutation on actions of univalent and bivalent kappa and delta ligands
Michael A. Ansonoff, Philip S. Portoghese and John E. Pintar
169-177
Original Investigation
Attenuation of cocaine-induced reinstatement of drug seeking in squirrel monkeys: kappa opioid and serotonergic mechanisms
Daniela Rüedi-Bettschen, James K. Rowlett, Roger D. Spealman and Donna M. Platt
179-188
Original Investigation
Regulation of cocaine-reinstated drug-seeking behavior by κ-opioid receptors in the ventral tegmental area of rats
WenLin Sun, YueQiang Xue, ZaiFang Huang and Jeffery D. Steketee
189-198
Original Investigation
Effectiveness of analogs of the kappa opioid receptor antagonist (3R)-7-Hydroxy-N-((1S)-1-{[(3R,4R)-4-(3-hydroxyphenyl)-3,4-dimethyl-1-piperidinyl]methyl}-2-methylpropyl)-1,2,3,4-tetrahydro-3-isoquinolinecarboxamide (JDTic) to reduce U50,488-induced diuresis and stress-induced cocaine reinstatement in rats
Patrick M. Beardsley, Gerald T. Pollard, James L. Howard and F. Ivy Carroll
199-209
Original Investigation
Endogenous kappa-opioid mediation of stress-induced potentiation of ethanol-conditioned place preference and self-administration
Robin E. Sperling, Stacey M. Gomes, Elizabeth I. Sypek, Amanda N. Carey and Jay P. McLaughlin
211-220
Original Investigation
Alteration of intravenous nicotine self-administration by opioid receptor agonist and antagonists in rats
Naila Ismayilova and Mohammed Shoaib
221-229
Original Investigation
Nicotine withdrawal and κ-opioid receptors
Michael J. McCarthy, Hailing Zhang, Norton H. Neff and Maria Hadjiconstantinou
231-240
Original Investigation
The effects of kappa-opioid receptor ligands on prepulse inhibition and CRF-induced prepulse inhibition deficits in the rat
Hugo A. Tejeda, Vladimir I. Chefer, Agustin Zapata and Toni S. Shippenberg
241-252
Original Investigation
Depressive-like effects of the kappa opioid receptor agonist salvinorin A are associated with decreased phasic dopamine release in the nucleus accumbens
Stephanie R. Ebner, Mitchell F. Roitman, David N. Potter, Anna B. Rachlin and Elena H. Chartoff
253-262
Original Investigation
The discriminative effects of the κ-opioid hallucinogen salvinorin A in nonhuman primates: dissociation from classic hallucinogen effects
Eduardo R. Butelman, Szymon Rus, Thomas E. Prisinzano and Mary Jeanne Kreek
263-274
Original Investigation
Role of kappa-opioid receptors in the effects of salvinorin A and ketamine on attention in rats
Christina L. Nemeth, Tracie A. Paine, Joseph E. Rittiner, Cécile Béguin and F. Ivy Carroll, et al.
275-284
Original Investigation
Kappa opioid mediation of cannabinoid effects of the potent hallucinogen, salvinorin A, in rodents
D. Matthew Walentiny, Robert E. Vann, Jonathan A. Warner, Lindsey S. King and Herbert H. Seltzman, et al.
285-294
Original Investigation
Effect of the selective kappa-opioid receptor antagonist JDTic on nicotine antinociception, reward, and withdrawal in the mouse
K. J. Jackson, Frank Ivy Carroll, S. S. Negus and M. I. Damaj
295-302
Original Investigation
Comparison of the kappa-opioid receptor antagonist DIPPA in tests of anxiety-like behavior between Wistar Kyoto and Sprague Dawley rats
Gregory V. Carr and Irwin Lucki