E-learning is the fastest-growing technology application in university education and business training. Making these electronic systems accessible to students and faculty with disabilities requires attention both to the courseware infrastructure or learning platform and to the content or subject material that the instructor places in that learning space. Increasing attention is finally being focused on making the courseware accessible. Because most systems are Web-based, this is usually a matter of good Web design and of designing a platform that facilitates faculty designing accessible content. Next, work is needed in assisting faculty to understand and design accessible content and in persuading institutions to develop institution-wide policies to support accessibility to e-learning for students with disabilities.