Special Issue: Oncogenetics: Achievements and Challenges
Guest Editors: Lucie Marisa Bucci and Jaques Simard
1
Oncogenetics and Interdisciplinary Collaborations: Essential for Progress
Henry T. Lynch
3-13
Partnering in Oncogenetic Research – The INHERIT BRCAs Experience: Opportunities and Challenges
Denise Avard, Peter Bridge, Lucie M. Bucci, Jocelyne Chiquette and Michel Dorval, et al.
15-20
BRCA1 and BRCA2 Mutations in Breast and Ovarian Cancer Syndrome: Reflection on the Creighton University Historical Series of High Risk Families
Olga M. Sinilnikova, Sylvie Mazoyer, Colette Bonnardel, Henry T. Lynch and Steven A. Narod, et al.
21-28
The Value of Multi-Modal Gene Screening in HNPCC in Quebec: Three Mutations in Mismatch Repair Genes that would have not been Correctly Identified by Genomic DNA Sequencing Alone
Susan McVety, Lili Li, Isabelle Thiffault, Philip H. Gordon and Elizabeth MacNamara, et al.
29-34
Mutational Targets in Colorectal Cancer Cells with Microsatellite Instability
Jacques Bertholon, Qing Wang, Carlos Maria Galmarini and Alain Puisieux
35-47
Challenges Identifying Genetic Determinants of Pediatric Cancers – the Childhood Leukemia Experience
Daniel Sinnett, Damian Labuda and Maja Krajinovic
49-54
Analysis of p27Kip1 Expression in Insulinomas Developed in Pancreatic β-cell Specific Men1 Mutant Mice
Sandra Fontanière, Huguette Casse, Philippe Bertolino and Chang Xian Zhang
55-59
The Challenge of Developing Evidence-Based Genetics Health Care in Practice
Brenda J. Wilson
61-75
Psychological Impact of Genetic Counseling for Familial Cancer: A Systematic Review and Meta-Analysis
Dejana Braithwaite, Jon Emery, Fiona Walter, A. Toby Prevost and Stephen Sutton
77-88
An Analysis of Unclassified Missense Substitutions in Human BRCA1
Sean V. Tavtigian, Paul B. Samollow, Deepika de Silva and Alun Thomas
89-93
Insights into the Molecular Basis of Human Hereditary Breast Cancer from Studies of the BRCA1 BRCT Domain
J. N. Mark Glover
95-102
The European Opposition Against the BRCA Gene Patents*
Gert Matthijs
103-116
Guidelines for Disclosing Genetic Information to Family Members: From Development to Use
Béatrice Godard, Thierry Hurlimann, Martin Letendre, Nathalie Égalité and INHERIT BRCAs
117-121
Democratising Access to Genetic Services
Bryn Williams-Jones and Michael M. Burgess