Update in Cancer Genetics: Clinical Translation
Guest Editor: Henry T. Lynch
1-2
Foreword
Henry T. Lynch
3-4
A hereditary cancer syndrome seminar: perspective of a Continuing Medical Education (CME) Director
Sally C. O’Neill
5-14
Roles and responsibilities of a medical geneticist
Wendy S. Rubinstein
15-26
Pathology of the hereditary colorectal carcinoma
Zoran Gatalica and Emina Torlakovic
27-39
Hereditary colorectal cancer syndromes: molecular genetics, genetic counseling, diagnosis and management
Henry T. Lynch, Jane F. Lynch, Patrick M. Lynch and Thomas Attard
41-52
The biochemical basis of microsatellite instability and abnormal immunohistochemistry and clinical behavior in Lynch Syndrome: from bench to bedside
C. Richard Boland, Minoru Koi, Dong K. Chang and John M. Carethers
53-58
Hereditary gynecologic cancers: differential diagnosis, surveillance, management and surgical prophylaxis
Karen H. Lu
59-64
Chemoprevention with special reference to inherited colorectal cancer
Patrick M. Lynch
65-72
Standards of care in diagnosis and testing for hereditary colon cancer
Patrick M. Lynch
73-82
Open AccessHereditary diffuse gastric cancer: association with lobular breast cancer
Kasmintan A. Schrader, Serena Masciari, Niki Boyd, Sara Wiyrick and Pardeep Kaurah, et al.
83-89
Hereditary breast cancer: pathobiology, clinical translation, and potential for targeted cancer therapeutics
Wendy S. Rubinstein
91-95
Genetic counseling and clinical management of newly diagnosed breast cancer patients at genetic risk for BRCA germline mutations: perspective of a surgical oncologist
Edibaldo Silva
97-102
Hereditary neoplasia syndromes and the role of the surgeon
Lisa C. Coviello and Robert A. Wascher
103-112
Pancreatic cancer and the FAMMM syndrome
Henry T. Lynch, Ramon M. Fusaro, Jane F. Lynch and Randall Brand