The incidence of primary central nervous system lymphoma (PCNSL), once a rare tumour, has risen significantly in both immunocompetent
and immunosuppressed patients. Although infiltration of the basal ganglia is not uncommon in PCNSL, extrapyramidal movement
disorders are generally not recognised as a mode of clinical presentation of this type of cerebral tumour. We present the
unusual case of a 75-year-old man who developed a parkinsonian syndrome of “pure akinesia” due to autopsy-confirmed PCNSL
primarily involving the globus pallidus bilaterally. Parkinsonism due to bilateral pallidal lesions is known but rare, and
such cases help in the understanding of basal ganglia function with regard to akinesia and freezing.
Key words Parkinsonism - Akinesia - Lymphoma
Received: 17 August 1998 Received in revised form: 13 April 1999 Accepted: 27 April 1999