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Abstract

Background  

Gentamicin is a common cause of allergic contact dermatitis but immediate (type 1) hypersensitivity is unusual.

Aims and methods  

We report a case of anaphylaxis to gentamicin in a 69-year-old man who developed urticaria, hypotension and loss of consciousness within minutes of receiving intravenous gentamicin.

Results  

The patient was successfully resuscitated and made a full recovery. Prick testing and patch testing to gentamicin was positive.

Conclusions  

Although allergic reactions to gentamicin are well recognised, there are few reported cases of anaphylaxis to gentamicin.

Keywords  Anaphylaxis - Drug allergy - Gentamicin - Neomycin

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