A sample of 522 middle and high school students from a school district in a northeastern state in the U.S. was used to address two questions about bullying and sexual harassment: Is one more frequent than the other, and are there gender or sexual orientation differences in this regard? And, does one have greater adverse health effects than the other, and, if so, for whom? Bullying occurred more frequently than sexual harassment for both girls and boys but not among sexual minorities. Girls were bullied or harassed as frequently as boys, but sexual minorities experienced higher levels of both. Compared to bullying, sexual harassment had adverse effects on more health outcomes. These adverse effects were especially notable among girls and sexual minorities.