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European Association for the Study of Diabetes
Commentary
E. R. Pearson
Journal Article
The T allele of rs7903146 TCF7L2 is associated with impaired insulinotropic action of incretin hormones, reduced 24 h profiles of plasma insulin and glucagon, and increased hepatic glucose production in young healthy men
K. Pilgaard, C. B. Jensen, J. H. Schou, V. Lyssenko and L. Wegner, et al.
Diabetologia, 2009, Volume 52, Number 7, Pages 1298-1307
Impaired glucagon-like peptide-1-induced insulin secretion in carriers of transcription factor 7-like 2 (TCF7L2) gene polymorphisms
S. A. Schäfer, O. Tschritter, F. Machicao, C. Thamer and N. Stefan, et al.
Diabetologia, 2007, Volume 50, Number 12, Pages 2443-2450
Protocol
Identification of a Common Variant Affecting Human Episodic Memory Performance Using a Pooled Genome-Wide Association Approach: A Case Study of Disease Gene Identification
Traci L. Pawlowski and Matthew J. Huentelman
Methods in Molecular Biology, 1, Volume 700, Disease Gene Identification, Part 4, Pages 261-269
In vitro modulation of TCF7L2 gene expression in human pancreatic cells
Keynoosh Khalooghi, Saeid Hashemi, Nahid Mehraban, Parvin Amiri and Javad Tavakkoly Bazzaz, et al.
Molecular Biology Reports, 2009, Volume 36, Number 8, Pages 2329-2332
The −590 IL-4 promoter polymorphism in patients with rheumatoid arthritis
Andrzej Pawlik, Joanna Wrzesniewska, Marcin Florczak, Barbara Gawronska-Szklarz and Magdalena Herczynska
Rheumatology International, 2005, Volume 26, Number 1, Pages 48-51
Carriers of the TCF7L2 rs7903146 TT genotype have elevated levels of plasma glucose, serum proinsulin and plasma gastric inhibitory polypeptide (GIP) during a meal test
A. P. Gjesing, L. L. Kjems, M. A. Vestmar, N. Grarup and A. Linneberg, et al.
Diabetologia, 2011, Volume 54, Number 1, Pages 103-110
Newly identified loci highlight beta cell dysfunction as a key cause of type 2 diabetes: Where are the insulin resistance genes?
J. C. Florez
Diabetologia, 2008, Volume 51, Number 7, Pages 1100-1110
Effects of the diabetes linked TCF7L2 polymorphism in a representative older population
David Melzer, Anna Murray, Alison J Hurst, Michael N Weedon and Stefania Bandinelli, et al.
BMC Medicine, 2006, Volume 4, Number 1, 34
A promoter SNP (–1323T>C) in G-substrate gene (GSBS) correlates with hypercholesterolemia
Shuji Ono, Yoichi Ezura, Mitsuru Emi, Yuko Fujita and Daisuke Takada, et al.
Journal of Human Genetics, 2003, Volume 48, Number 9, Pages 447-450
Association of variants of the TCF7L2 gene with increases in the risk of type 2 diabetes and the proinsulin:insulin ratio in the Spanish population
J. L. González-Sánchez, M. T. Martínez-Larrad, C. Zabena, M. Pérez-Barba and M. Serrano-Ríos
Diabetologia, 2008, Volume 51, Number 11, Pages 1993-1997
Keywords Genetics - Glucagon - Hepatic glucose production - Incretin hormones - Insulin secretion - TCF7L2 - Type 2 diabetes
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