A meshless simulation system is presented for elastic deformation driven by skeleton in this paper. In this system, we propose a new method for calculating node rotation while applying a similar technique with stiffness warping to tackle the nonlinear large deformation. In our method, all node rotations are evaluated from sampling points in attached skeleton by constructing and solving the diffusion partial differential equation. The experiments indicated that the method can enhance the stability of the dynamics and avoid fussy sub-step calculation in static deformation edition. Moreover, rational deformation results for the area around the skeleton joints can be simulated without user interaction by adopting the simplified technique.