Vaginal biopsy specimens from premenopausal women with uterine myoma were studied by immunohistochemical methods using monoclonal
antibodies to the differentiation antigens before and after hysterectomy. Immunocompetent cells (mainly CD8
+ antigens) were detected in vaginal mucosa of controls and were virtually absent from specimens from the patients with uterine
myoma. The content of immunocompetent cells in the vaginal mucosa did not change for at least 12 months after hysterectomy
irrespective of the scope of intervention.
Key Words
immunohistochemistry
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vagina
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local immunity
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myoma
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hysterectomy
Translated fromByulleten' Eksperimental'noi Biologii i Meditsiny, vol. 126, No. 10, pp. 436–440, October, 1998