Anal fissure management has rapidly progressed in the last 15 years as our understanding of fissure pathophysiology has developed.
All methods of treatment aim to reduce the anal sphincter spasm associated with chronic anal fissures. Surgical techniques
have been used for over 100 years with success. Lateral internal sphincterotomy remains the surgical treatment of choice for
many practitioners. Postoperative impairment of continence remains controversial. Recently, less invasive methods of treatment
have been explored. Topical nitrates, calcium channel blockers and botulinum toxin are established treatments. These and other
non-surgical treatments are described in this review. Various guidelines and treatment algorithms for anal fissure are also
discussed.
Key words Anal fissure - Fissure in ano - Sphincterotomy - Anal stretch - Anal dilatation - Nitrate - Glyceryl trinitrate - Calcium channel blocker - Botulinum toxin