Coronary artery calcium (CAC) accumulation, a marker of atherosclerosis burden, differs significantly among patients of different
ethnicities. It has been proposed that CAC scores can be used to assess the number of life years lost or gained by an individual
with a given amount of coronary artery calcium. Therefore, we sought to develop a method to calculate the coronary age of
an individual based on the extent of CAC in this subject compared to that of individuals of the same race, age and sex. We
used median CAC scores from previously published data from the Multi-Ethnic Study of Atherosclerosis (MESA) to derive the
predicted coronary age of subjects from 4 ethnic groups (White, Black, Hispanic and Chinese) of both sexes. With this method
a 50-year-old white man with a CAC score of 40 has a coronary age of a 61-year-old white man; for a black man with a score
of 40 the coronary age is 70. This method should allow patients to better understand the prognostic significance of their
test results and may ensure a better compliance with preventive regimens.
Keywords Coronary artery calcium score - Ageing - Atherosclerosis - Outcome