The interoperability problem arises in heterogeneous systems where different data sources coexist and there is a need for meaningful information sharing. One of the most representive realms of diversity of data representation is the spatio-temporal domain. Spatio-temporal data are most often described according to multiple and greatly diverse perceptions or viewpoints, using different terms and with heterogeneous levels of detail. Reconciling this heterogeneity to build a fully integrated database is known to be a complex and currently unresolved problem, and few formal approaches exist for the integration of spatio-temporal databases. The paper discusses the interoperation issue in the context of conceptual schema integration. Our proposal relies on two well-known formalisms: conceptual models and description logics. The MADS conceptual model with its multiple representation capabilities allows to fully describe semantics of the initial and integrated spatio-temporal schemas. Description logics are used to express the set of inter-schema mappings. Inference mechanisms of description logics allow us to check the compatibility of the semantic mappings and to propose different structural solutions for the integrated schema.