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Compress® Periprosthetic Fractures: Interface Stability and Ease of Revision
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Symposium: Selected Papers Presented at the 2008 Meeting of the Musculoskeletal Tumor Society
Compress ® Periprosthetic Fractures: Interface Stability and Ease of Revision
Wakenda K. Tyler2, John H. Healey2, Carol D. Morris2, Patrick J. Boland2 and Richard J. O’Donnell1 
| (1) |
UCSF Helen Diller Family Comprehensive Cancer Center, Orthopaedic Oncology Service, 1600 Divisadero Street, 4th Floor, San Francisco, CA, 94115-1939, USA
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| (2) |
Memorial Sloan-Kettering Cancer Center, New York, NY,
USA |
Received: 26 December 2008 Accepted: 5 June 2009 Published online: 30 June 2009
Abstract Periprosthetic fractures after massive endoprosthetic reconstructions pose a reconstructive challenge and jeopardize limb
preservation. Compressive osseointegration technology offers the promise of relative ease of prosthetic revision, since fixation
is achieved by means of a short intramedullary device. We retrospectively reviewed the charts of 221 patients who had Compress ® devices implanted in two centers between December, 1996 and December, 2008. The mean followup was 50 months (range, 1–123 months).
Six patients (2.7%) sustained periprosthetic fractures and eight (3.6%) had nonperiprosthetic ipsilateral limb fractures occurring
from 4 to 79 months postoperatively. All periprosthetic fractures occurred in patients with distal femoral implants (6/154,
3.9%). Surgery was performed in all six patients with periprosthetic femur fractures and for one with a nonperiprosthetic
patellar fracture. The osseointegrated interface was radiographically stable in all 14 cases. All six patients with periprosthetic
fracture underwent limb salvage procedures. Five patients had prosthetic revision; one patient who had internal fixation of
the fracture ultimately underwent amputation for persistent infection. Periprosthetic fractures involving Compress ® fixation occur infrequently and most can be treated successfully with further surgery. When implant revision is needed, the
bone preserved by virtue of using a shorter intramedullary Compress ® device as compared to conventional stems, allows for less complex surgery, making limb preservation more likely.
Level of Evidence: Level IV, therapeutic study. See Guidelines for Authors for a complete description of levels of evidence.
Each author certifies that he or she has no commercial associations (eg, consultancies, stock ownership, equity interest,
patent/licensing arrangements, etc) that might pose a conflict of interest in connection with the submitted article.
Each author certifies that his or her institution has approved the human protocol for this investigation and that all investigations
were conducted in conformity with ethical principles of research, and that informed consent for participation in the study
was obtained.
This work was performed at the UCSF Helen Diller Family Comprehensive Cancer Center, San Francisco, CA.
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