Volume 10, Number 1, 39-47, DOI: 10.1007/s005210170016

A Comparison of State-of-the-Art Classification Techniques with Application to Cytogenetics

Boaz Lerner and Neil D. Lawrence

View Related Documents

Abstract

in situ hybridisation (FISH) signals. Highly-accurate classification of valid signals and artifacts of several cytogenetic probes (colours) is required for detecting abnormalities in FISH images. More than 3100 FISH signals are classified by each of the techniques into colour and as real or artifact with accuracies of around 98% and 88%, respectively. The results of the comparison also show a trade-off between simplicity represented by the naive Bayesian classifier, and high classification performance represented by the other techniques.

Keywords:Bayesian neural network; Fluorescence in situ hybridisation (FISH); Multilayer perceptron; Naive Bayesian classifier; Signal classification; Support vector machine

Fulltext Preview

Image of the first page of the fulltext document