Ginseng is the root of the perennial herbs which contain a series of tetracyclic triterpenoid saponins (ginsenosides) as active ingredients. It is considered a tonic or adaptogenic that enhances physical and sexual performance. To fulfill that study, the author hereby performed an in vitro study to assess the effect of ginseng on sperm count in vitro. Ten test and 10 control semen samples were used to assess the effect of aqueous ginseng extract.There is no significant difference of average sperm counts at 0 minutes for both groups but there is a significant difference of average sperm counts at 30 minutes. The control group show significant decreasing in the sperm count at 30 minutes. According to this study, the ginseng extract can help preserve the sperm count.