A new cyclic peptide, prepatellamide A (
1), along with three known cyclic peptides (2)— (4), was isolated from the ascidian
Lissoclinum patella. The structure of prepatellamide A was determined from one- and two-dimensional
1H and
13C NMR spectra. The known cyclic peptides were identified as patellamides A (
2), B (
3) and C (
4).
Keywords ascidian -
Lissoclinum patella
- cyclopeptide - cytotoxicity