The identification of coding potential in DNA sequences is of major importance in bioinformatics, where it is often used to
assist expert systems that automatically try to recognize genes in genomes. For longer sequences, the identification of coding
potential tends to be easier due to a better signal-to-noise ratio, whereas for very short sequences the issue becomes more
problematic. In this paper, we present new methods that specifically aim at a better prediction of coding potential in short
sequences. To this end, we combine different, complementary sequence features together with a feature selection strategy.
Results comparing the new classifiers to state of the art models show that our new approach significantly outperforms the
existing methods when applied to short sequences.