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Results of a Minimally Invasive Technique for Treatment of Unicameral Bone Cysts
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Clinical Research
Results of a Minimally Invasive Technique for Treatment of Unicameral Bone Cysts
Gökçe Mik1  , Alexandre Arkader3, Alexander Manteghi2 and John P. Dormans4, 5
| (1) |
Department of Orthopaedic Surgery, Istanbul Cerrahi Hastanesi, Istanbul, Turkey |
| (2) |
Department of Orthopaedics, The Children’s Hospital of Philadelphia, Philadelphia, PA, USA |
| (3) |
Children’s Orthopaedic Center, Children’s Hospital Los Angeles, and Keck School of Medicine, University of Southern California, Los Angeles, CA, USA |
| (4) |
Department of Orthopaedic Surgery, University of Pennsylvania School of Medicine, Philadelphia, PA, USA |
| (5) |
Department of Orthopaedic Surgery, The Children’s Hospital of Philadelphia, 2nd Floor Wood Center, 34th and Civic Center Blvd, Philadelphia, PA 19104-4399, USA |
Received: 1 October 2008 Accepted: 17 July 2009 Published online: 4 August 2009
Abstract Unicameral bone cysts are benign bone lesions commonly seen in pediatric patients. Several treatment methods have been described
with variable results and high recurrence rates. We previously reported short-term success of a minimally invasive technique
that includes combining percutaneous decompression and grafting with medical-grade calcium sulfate pellets. The purpose of
this study was to review the additional long-term results with a minimum followup of 24 months (average, 37 months; range,
24–70 months). We identified 55 patients with an average age of 10.8 years (range, 1.3–18 years). Forty-one of 55 lesions
occurred in the humerus and femur. Forty-four of 55 (80%) patients had a partial or complete response after initial surgery;
of these, seven obtained a partial or complete response after a repeat surgery (cumulative healing rate, 94%). Two patients
underwent a third surgery (cumulative healing rate, 98%). One underwent a third repeat surgery (cumulative healing rate, 100%).
There were no major complications associated with the procedure. Two patients had a superficial infection that resolved with
oral antibiotics. Although some patients required a repeat procedure, complete or partial response at a minimum 24 months’
followup was achieved in all patients.
Level of Evidence: Level IV, therapeutic study. See Guidelines for Authors for a complete description of levels of evidence.
Each author certifies that he or she has no commercial associations (eg, consultancies, stock ownership, equity interest,
patent/licensing arrangements, etc) that might pose a conflict of interest in connection with the submitted article.
Each author certifies that his or her institution has approved the human protocol for this investigation, that all investigations
were conducted in conformity with ethical principles of research, and that informed consent for participation in the study
was obtained.
This work was performed at The Children’s Hospital of Philadelphia.
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