DNA isolated from different T phages served as a better template for the synthetic activity of unmodified
Escherichia coli RNA polymerase in the
in vitro system than did the host DNA. cAMP significantly stimulated the activity of such a preparation of RNA polymerase. The stimulation
was more pronounced with the host DNA template than with phage DNA. However, the synthetic activity of
Escherichia coli RNA polymerase was greater in the presence of cAMP than without it when phage DNA served as the template.