.
Photodynamic therapy (PDT) is an anticancer combination therapy, which requires a photosensitiser, which tends to accumulate
preferentially in the tumour, and light. Historically large, complex lasers have been used to carry out PDT treatment. Nowadays
there is a wide range of coherent and non-coherent sources that can be used. This paper considers the important characteristics
of light sources for PDT, including dye lasers pumped by argon or metal vapour lasers and frequency-doubled Nd:YAG lasers.
Non-laser sources including tungsten filament, xenon arc, metal halide and fluorescent lamps are also discussed. New exiciting
developments such as LEDs and femtosecond lasers are also reviewed. The relative merits of laser and non-laser sources are
critically examined.
Keywords: Cancer treatment; Light sources; Photodynamic therapy (PDT); Photosensitisers
Paper received 18 June 2001; accepted 6 December 2001.