The economic assessment of industrial accidents caused by abnormal behaviors can not only improve the risk assessment results but also serve as a crucial criterion for prioritizing the correction plans. Three stages of works are designed to derive the loss figures from assessing the standard operation procedure. The objective of stage one is to identify potential abnormal behaviors through analysis of activities. The objective of stage 2 is to identify cost types initiated by different accident losses. The objective of stage 3 is to establish the accident cost bank through analyzing the historical accident data. Two industrial cases, including one semiconductor and one steel company, were studies to demonstrate the feasibility of this approach in both high-tech and traditional industry. This study proposes a framework to develop abnormal behavior identification and cost estimation model.