Accessibility tries to avoid introducing in web pages any kind of barriers that might prevent their being understood by disabled users. Content Management Systems are a widespread class of products that enable the creation, archiving and publishing of information on web. This paper discusses how to relate accessibility with CMS, starting from some key functions of this family of products. This requires analysing some aspects which are sometimes very remote from a technological perspective, but closer and more related to the environment in which they are used. Many of them are suggested by experience, and need to be correctly reformulated in order to be included in the life cycle of a CMS.