Molecular Pain

Min Zhuo

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Contents
ESM

i-xiv
Front matter
3-40
Part I / Genes, Neurons and Neurotransmission
3-40
Front matter
3-15
Genes and Neurons
17-26
Synapses: Coupling of Presynaptic Voltage-gated Ca²⁺ Channels to Vesicular Release of Neurotransmitter
27-40
Synaptic Vesicle Cycle at Nerve Terminals
43-106
Part II / Glutamate, Excitatory Transmission and Pain
43-106
Front matter
43-52
Postsynaptic Excitatory Transmission
53-62
Kainate Receptors
63-84
Excitatory Amino Acid Neurotransmitter Regulation
85-95
Spinal Glutamate Receptors
97-106
Glutamate Kainate Receptor in Pain Transmission and Modulation
109-154
Part III / Neuropeptides, ATP, Retrograde Messengers and Opioids
109-154
Front matter
109-115
Neuropeptides
117-130
ATP and Its Receptors in Pain
131-143
Opioid Receptors
145-154
Retrograde Messengers
157-184
Part IV / Inhibitory Transmission and Plasticity
157-184
Front matter
157-168
Inhibitory Transmission
169-184
Plasticity of Inhibition; GABA/glycine System
187-244
Part V / Postsynaptic Signaling and Gene Regulation
187-244
Front matter
187-205
Protein Kinases and Phosphatases
207-217
Activity-dependent Gene Regulation: How Do Synapses Talk to the Nucleus and Fine-tune Neuronal Qutputs?
219-234
Second Messenger Pathways in Pain
235-244
Genetic Approaches for the Study of Pain
247-292
Part VI / Peripheral Nociceptor, Amygdala and Fear
247-292
Front matter
247-263
Peripheral Nociceptors
265-279
Amygdala—Pain Processing and Pain Modulation
281-292
Fear Learning
295-333
Part VII / Spinal Plasticity, Reorganization and Chronic Pain
295-333
Front matter
295-307
Silent Glutamatergic Synapses and Long-term Facilitation in Spinal Dorsal Horn Neurons
309-324
Anatomical Changes in the Spinal Dorsal Horn after Peripheral Nerve Injury
325-333
Spinal Microglia in Neuropathic Pain Plasticity
337-369
Part VIII / Cortical Plasticity, Reorganization and Amputation
337-369
Front matter
337-349
ACC Plasticity
351-369
Reorganization of the Sensorimotor System after Injury
373-422
Part IX / Endogenous Analgesia and Other Form of Analgesia
373-422
Front matter
373-386
Endogenous Biphasic Modulation
387-396
Paradoxical Analgesic and Hyperalgesic Effects of Stress
397-411
Acupuncture Analgesia
413-422
Mechanisms of Opioid Tolerance
425-480
Part X / Models for Studying Pain and Searching for Pain Killers
425-480
Front matter
425-439
Models in Pain Research
441-458
Models for Studying Pain and Searching for Pain Killers in Vitro Electrophysiological Studies of Pain
459-467
Whole-cell Patch-clamp Recording in Vivo
469-480
Basic Mechanisms of Clinically Used Drugs
481-501
Back matter

About This Book

Title

Molecular Pain

Editor

Min Zhuo(1)

Editor Affiliations

University of Toronto Department of Physiology Medical Sciences Bldg, Rm 3342 1 King’s College Circle Toronto Ontario Canada M5S 1A8

Collection

Medicine

Subjects

Copyright Year

2007

DOI

10.1007/978-0-387-75269-3

ISBN

978-0-387-75268-6 (Print) 978-0-387-75269-3 (Online)

Additional Links

About This Book

Publisher

Springer New York

SpringerLink Date

Sunday, February 08, 2009

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