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Brendan Barrett and Patrick Parfrey
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Front matter
1-17
On Framing the Research Question and Choosing the Appropriate Research Design
19-37
Longitudinal Studies and Determination of Risk
39-60
Modeling Longitudinal Data, I: Principles of Multivariate Analysis
61-94
Modeling Longitudinal Data, II: Standard Regression Models and Extensions
95-111
The Design of Randomized Controlled Trials
113-126
Analysis of Randomized Controlled Clinical Trials
127-136
Evaluation of Diagnostic Tests
137-154
Biomarkers and Surrogates in Clinical Studies
155-169
Measurement and Analysis of Patient-Reported Outcomes
171-186
Bias in Clinical Studies of Genetic Diseases
187-201
Genetic Epidemiology of Complex Phenotypes
203-215
Qualitative Research in Clinical Epidemiology
217-233
Primer on Systematic Review and Meta-Analysis
235-250
The Role of Health Economics within Clinical Research
251-261
Development and Limitations of Clinical Practice Guidelines
263-283
Basics of Health Technology Assessment
285-297
Research Ethics for Clinical Researchers
299-311
Budgeting, Funding and Managing Clinical Research Projects
313-321
Back matter
Patrick Parfrey and Pietro Ravani
Sean W. Murphy
Pietro Ravani, Brendan Barrett and Patrick Parfrey
Bryan M. Curtis, Brendan J. Barrett and Patrick S. Parfrey
Robert N. Foley
John M. Fardy
Claudio Rigatto and Brendan J. Barrett
Klemens B. Meyer and Kimberly A. Clayton
Susan Stuckless and Patrick S. Parfrey
Lynette Peddle and Proton Rahman
Deborah M. Gregory and Christine Y. Way
Marcello Tonelli, Dan Hackam and Amit X. Garg
Braden J. Manns
Bruce Culleton
Daria OReilly, Kaitryn Campbell and Ron Goeree
John D. Harnett and Richard Neuman
Elizabeth Hatfield, Elizabeth Dicks and Patrick Parfrey
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