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Biomedical and Life Sciences

Regulation of Gene Expression
Molecular Mechanisms

Gary H. Perdew, John P. Vanden Heuvel and Jeffrey M. Peters

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Contents
ESM

i-ix
Front matter
3-140
I / Gene Expression Control At The Mrna Level
3-140
Front matter
3-9
Overview
11-30
Messenger RNA Accumulation
31-48
Transcript Profiling
49-103
Transcriptional Regulation of Gene Expression
105-140
Posttranscriptional Processing of Messenger RNA
149-258
II / Regulation Of Protein Levels And Transcription Factor Function
149-258
Front matter
149-153
Overview
155-160
Protein Synthesis and Turnover
161-172
Proteomics
173-214
Determination of Protein-Protein Interactions and the Motifs That Mediate Them
215-238
Posttranslational Modifications
239-258
Dissection of Signaling Pathways
267-320
III / Use Of Transgenic And Knockout Mice To Study Gene Regulation
267-320
Front matter
267-269
Overview
271-293
Production of Transgenic Animals
295-318
Knockout Animals
319-320
Isolation of Cells and Cell Lines From Transgenic and Knockout Animals
329-333
Back matter

About This Book

Title

Regulation of Gene Expression
Molecular Mechanisms

Editors

Editor Affiliations

The Pennsylvania State University Center for Molecular Toxicology and Carcinogenesis Department of Veterinary and Biomedical Sciences University Park PA

Collection

Biomedical and Life Sciences

Subjects

Copyright Year

2007

DOI

10.1007/978-1-59745-228-1

ISBN

978-1-58829-265-0 (Print) 978-1-59745-228-1 (Online)

Additional Links

About This Book

Publisher

Humana Press

SpringerLink Date

Sunday, August 17, 2008

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