i-xii
Front matter
1-32
Design and Implementation of High-Throughput Screening Assays
Ricardo Macarrón and Robert P. Hertzberg
33-54
Creation of a Small High-Throughput Screening Facility
Tod Flak
55-68
Informatics in Compound Library Management
Mark Warne and Louise Pemberton
69-106
Statistics and Decision Making in High-Throughput Screening
Isabel Coma, Jesus Herranz and Julio Martin
107-126
Enzyme Assay Design for High-Throughput Screening
Kevin P. Williams and John E. Scott
127-143
Application of Fluorescence Polarization in HTS Assays
Xinyi Huang and Ann Aulabaugh
145-158
Screening G Protein-Coupled Receptors: Measurement of Intracellular Calcium Using the Fluorometric Imaging Plate Reader
Renee Emkey and Nancy B. Rankl
159-186
High-Throughput Automated Confocal Microscopy Imaging Screen of a Kinase-Focused Library to Identify p38 Mitogen-Activated Protein Kinase Inhibitors Using the GE InCell 3000 Analyzer
O. Joseph Trask, Debra Nickischer, Audrey Burton, Rhonda Gates Williams and Ramani A. Kandasamy, et al.
187-208
Recent Advances in Electrophysiology-Based Screening Technology and the Impact upon Ion Channel Discovery Research
Andrew Southan and Gary Clark
209-223
Automated Patch Clamping Using the QPatch
Kenneth A. Jones, Nicoletta Garbati, Hong Zhang and Charles H. Large
225-237
High-Throughput Screening of the Cyclic AMP-Dependent Protein Kinase (PKA) Using the Caliper Microfluidic Platform
Leonard J. Blackwell, Steve Birkos, Rhonda Hallam, Gretchen Van De Carr and Jamie Arroway, et al.
239-257
Use of Primary Human Cells in High-Throughput Screens
Angela Dunne, Mike Jowett and Stephen Rees
259-268
Back matter