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Artificial Immune System for Classification of Cancer

Shin Ando14 Contact Information and Hitoshi Iba15 Contact Information

(14)  Dept. of Electronics Engineering, School of Engineering University of Tokyo, Japan
(15)  Dept. of Frontier Informatics, School of Frontier Science, University of Tokyo, Japan
Abstract
This paper presents a method for cancer type classification based on microarray-monitored data. The method is based on artificial immune system(AIS), which utilizes immunological recognition for classification. The system evolutionarily selects important genes; optimize their weights to derive classification rules. This system was applied to gene expression data of acute leukemia patients to classify their cancer class. The primary result found few classification rules which correctly classified all the test samples and gave some interesting implications for feature selection principles.

Contact Information Shin Ando
Email: ando@miv.t.u-tokyo.ac.jp

Contact Information Hitoshi Iba
Email: iba@miv.t.u-tokyo.ac.jp
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Referenced by
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  1. Banerjee, Mohua (2007) . IEEE Transactions on Systems Man and Cybernetics Part C (Applications and Reviews) 37(4)
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