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Programmable Infusion Pumps in ICUs: An Analysis of Corresponding Adverse Drug Events

Teryl K. Nuckols, Anthony G. Bower, Susan M. Paddock, Lee H. Hilborne, Peggy Wallace, Jeffrey M. Rothschild, Anne Griffin, Rollin J. Fairbanks, Beverly Carlson and Robert J. Panzer, et al.

From the issue entitled "New Medical Technologies: The Potential and Pitfalls of Innovation, Guest Editors: Jeffrey A. Tice, MD, Mitchell D. Feldman, MD, MPhil, Deputy Editors: Richard M. Hoffman, MD, MPH, Claudia A. Steiner, MD, MPH"

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Abstract

Background  

Patients in intensive care units (ICUs) frequently experience adverse drug events involving intravenous medications (IV-ADEs), which are often preventable.

Objectives  

To determine how frequently preventable IV-ADEs in ICUs match the safety features of a programmable infusion pump with safety software (“smart pump”) and to suggest potential improvements in smart-pump design.

Design  

Using retrospective medical-record review, we examined preventable IV-ADEs in ICUs before and after 2 hospitals replaced conventional pumps with smart pumps. The smart pumps alerted users when programmed to deliver duplicate infusions or continuous-infusion doses outside hospital-defined ranges.

Participants  

4,604 critically ill adults at 1 academic and 1 nonacademic hospital.

Measurements  

Preventable IV-ADEs matching smart-pump features and errors involved in preventable IV-ADEs.

Results  

Of 100 preventable IV-ADEs identified, 4 involved errors matching smart-pump features. Two occurred before and 2 after smart-pump implementation. Overall, 29% of preventable IV-ADEs involved overdoses; 37%, failures to monitor for potential problems; and 45%, failures to intervene when problems appeared. Error descriptions suggested that expanding smart pumps’ capabilities might enable them to prevent more IV-ADEs.

Conclusion  

The smart pumps we evaluated are unlikely to reduce preventable IV-ADEs in ICUs because they address only 4% of them. Expanding smart-pump capabilities might prevent more IV-ADEs.

KEY WORDS  drug therapy - medication error - prevention and control - infusion pump - decision making - computer-assisted - critical care

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