An integrated approach of mining association rules and meta-rules based on a hyper-structure is put forward. In this approach, time serial databases are partitioned according to time segments, and the total number of scanning database is only twice. In the first time, a set of 1-frequent itemsets and its projection database are formed at every partition. Then every projected database is scanned to construct a hyper-structure. Through mining the hyper-structure, various rules, for example, global association rules, meta-rules, stable association rules and trend rules etc. can be obtained. Compared with existing algorithms for mining association rule, our approach can mine and obtain more useful rules. Compared with existing algorithms for meta-mining or change mining, our approach has higher efficiency. The experimental results show that our approach is very promising.