We assessed the effectiveness of national and international wildlife trade regulations in Asia by surveying four wildlife markets in Myanmar for bears and bear parts. Bears are protected in Myanmar and neighbouring countries, and are included in CITES Appendix I, precluding international trade. Three of the four wildlife markets were situated at the border with neighbouring countries (China and Thailand) whereas the fourth, situated in Myanmar’s interior, also catered to international markets. During seven checks (1999–2006) we recorded 1,200 bear parts, representing a minimum of 215 individual bears. Most items were from Asiatic black bears Ursus thibetanus but also sun bear Helarctos malayanus parts were offered for sale. There were significant temporal and spatial differences in what items were offered for sale. Prices were low (USD 4–40 per item) and the total monetary value of the items for sale was USD 6,500–9,500 (not including gall bladders). Carcasses, skulls, canines, paws, claws, whole skins, pieces of skin, gall bladders and derivates, were openly displayed, with vendors being frank about prices, origin, and potential buyers. Only in the interior were prices quoted in the local currency; at the other three markets currencies of the neighbouring countries were used. Legal (international) trade in bears or bear parts from Myanmar is virtually non-existent, and the observed trade in bear parts strongly indicates a serious lack of enforcement effort. International trade in bear parts from Myanmar is significant, and open, and we conclude that the enforcement of wildlife trade regulations, at least when they concerns bear species, have by and large failed.