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Published in partnership with the
European Association for the Study of Diabetes
Commentary
W. W. Winder
Journal Article
Targeting skeletal muscle AMP-activated protein kinase to treat type 2 diabetes
Eric B. Taylor and Laurie J. Goodyear
Current Diabetes Reports, 2007, Volume 7, Number 6, Pages 399-401
Overexpression of CYP2E1 induces HepG2 cells death by the AMP kinase activator 5′-aminoimidazole-4-carboxamide-1-β-d-ribofuranoside (AICAR)
Jian Zhuge
Cell Biology and Toxicology, 2009, Volume 25, Number 3, Pages 253-263
Insulin signalling downstream of protein kinase B is potentiated by 5′AMP-activated protein kinase in rat hearts in vivo
S. L. Longnus, C. Ségalen, J. Giudicelli, M. P. Sajan and R. V. Farese, et al.
Diabetologia, 2005, Volume 48, Number 12, Pages 2591-2601
Intravenous AICAR administration reduces hepatic glucose output and inhibits whole body lipolysis in type 2 diabetic patients
H. Boon, M. Bosselaar, S. F. E. Praet, E. E. Blaak and W. H. M. Saris, et al.
Diabetologia, 2008, Volume 51, Number 10, Pages 1893-1900
Stress signaling in the heart by AMP-activated protein kinase
Raymond Russell
Current Hypertension Reports, 2006, Volume 8, Number 6, Pages 446-450
Book Chapter
Modulation of O2 Sensitive K+ Channels by AMP-activated Protein Kinase
M.L. Dallas, J.L. Scragg, C.N. Wyatt, F. Ross and D.G. Hardie, et al.
Advances in Experimental Medicine and Biology, 1, Volume 648, Arterial Chemoreceptors, Pages 57-63
AMP-activated protein kinase in skeletal muscle: From structure and localization to its role as a master regulator of cellular metabolism
C. A. Witczak, C. G. Sharoff and L. J. Goodyear
Cellular and Molecular Life Sciences, 2008, Volume 65, Number 23, Pages 3737-3755
Maintaining Energy Balance in Health and Disease: Role of the AMP-Activated Protein Kinase
John W. Scott
Protein Reviews, 1, Volume 13, Post-Translational Modifications in Health and Disease, Pages 199-232
Role of hypothalamic 5′-AMP-activated protein kinase in the regulation of food intake and energy homeostasis
Min Seon Kim and Ki Up Lee
Journal of Molecular Medicine, 2005, Volume 83, Number 7, Pages 514-520
AMP-Activated Protein Kinase and Metabolic Control
Benoit Viollet and Fabrizio Andreelli
Handbook of Experimental Pharmacology, 1, Volume 203, Diabetes - Perspectives in Drug Therapy, Pages 303-330
Keywords AICAR - 5′-AMP-activated protein kinase - AMPK activators - Fatty acid turnover - Gluconeogenesis - Glucoregulation - Hepatic glucose production - Type 2 diabetes
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