We report a case of a successfully resected retroperitoneal benign schwannoma using laparoscopic surgery. A 62-year-old woman presented with an asymptomatic retroperitoneal mass. Computed tomography (CT) scan revealed a solid tumor compressing the inferior vena cava (IVC). First, we performed an intraoperative biopsy analysis, which revealed a benign neurologic tumor. We then proceeded with the complete laparoscopic resection of the tumor. Pathology revealed a benign schwannoma 8 2 5 cm in size. To our knowledge, only three other cases of the laparoscopic resection of retroperitoneal schwannoma have been reported. In our case, despite the large size of the tumor and the high level of compression of the IVC, a totally laparoscopic resection was feasible.