Volume 21, Number 7, 1031-1033, DOI: 10.1007/s00467-006-0054-1

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International Pediatric Nephrology Association

Steroid sparing effect of a herbal preparation in steroid-dependent nephrotic syndrome

Arpana Iyengar, Hrishikesh Damle, Chanda Kulkarni, Latha Damle and Kishore Phadke

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Abstract

Investigations on plants are revealing the potential therapeutic benefits of medicinal herbs in treating immunological disorders. Nephrotic syndrome has emerged as an immunological disorder. Steroid dependence poses a therapeutic challenge in the management of nephrotic syndrome. Our pilot study compares the efficacy of an ayurvedic polyherbal preparation ‘Shathavaryadi Yoga (NS001)' with oral cyclophosphamide in maintaining remission in steroid-dependent nephrotic syndrome.

Keywords  Cyclophosphamide - Cyclosporine - Herbal medicines

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