Volume 37, Number 3, 157-163, DOI: 10.1007/s10870-007-9178-9

Crystal structure of 1-(2,3:5,6-Di-O-isopropylidene-β-D-mannofuranosyl)-1H-[1,2,3]triazol-4,5-dicarboxylic acid diethyl ester

Harry Seibel, Penny L. Miner, Peter Norris and Timothy R. Wagner

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Abstract

The synthesis and X-ray crystal structure of 1-(2,3:5,6-di-O-isopropylidene-β-D-mannofuranosyl)-1H-[1,2,3]triazol-4,5-dicarboxylic acid diethyl ester are reported. It crystallizes in the orthorhombic system with space group P212121 (No. 19); a=8.6148(5), b=10.4793(6), c=24.6873(15) Å  and Z=4. The solid state structure verifies the β-anomeric form of the title compound and provides evidence for the structures of the azide and chloride precursors.

KEY WORDS  1,2,3-triazole - mannofuranose - anomeric configuration - dipolar cycloaddition

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