The fusion of computed tomography and magnetic resonance images is a software-dependent processing technique that enables
one to integrate and analyze preoperative images for planning complex musculoskeletal tumor resections. By integrating various
imaging modalities into one imaging data set we may facilitate preoperative image analysis and planning of navigation computer-assisted
bone tumor resection and reconstruction. We performed image fusion for computer-assisted tumor surgery in 13 consecutive patients,
seven males and six females, with a mean age of 35.8 years (range, 6–80 years). Visual verification of fused images was accurate
in all patients. The mean time for image fusion was 30.6 minutes (range, 8–80 minutes). After intraoperative registration,
all tumor resections were performed as planned preoperatively under navigation image guidance. Resections achieved after navigation
resection planning were validated by postoperative CT or resected specimens in seven patients. Histologic examination of all
resected specimens showed tumor-free margins in patients with bone sarcoma. The fusion of computed tomography and magnetic
resonance imaging has the potential to enhance computer-assisted bone tumor surgery. The fusion image, when combined with
surgical navigation, helps surgeons reproduce a preoperative plan reliably and may offer substantial clinical benefits.
Level of Evidence: Level IV, therapeutic study. See the Guidelines for Authors for a complete description of levels of evidence.
Each author certifies that he or she has no commercial associations (eg, consultancies, stock ownership, equity interest,
patent/licensing arrangements, etc) that might pose a conflict of interest in connection with the submitted article.
Each author certifies that his or her institution has approved the human protocol for this investigation, that all investigations
were conducted in conformity with ethical principles of research.