Volume 162, Numbers 1-2, 1-34, DOI: 10.1007/s00604-008-0947-8

Boronic acid based probes for microdetermination of saccharides and glycosylated biomolecules

Heike S. Mader and Otto S. Wolfbeis

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Abstract

This review covers the progress made in the development of fluorescent probes for saccharides and glycosylated biomolecules. Such probes are supposed to work at physiological pH and at room temperature, and preferably have fast responses. The modes of interactions between probe and saccharides are discussed, not the least with the aim to assist in the design of more selective probes for which there is a substantial need.

Keywords: Fluorescent probes; boronic acid probes; saccharide, glycoproteins

Correspondence: Otto S. Wolfbeis, Institute of Analytical Chemistry, Chemo- and Biosensors, University of Regensburg, 93040 Regensburg, Germany

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