The continuous-wave (CW) and acoustooptically (AO) Q-switched operation of a Tm (4 at %), Ho (0.4 at %):GdVO₄ laser at a 2.05-μm wavelength were reported in this paper. The Tm,Ho:GdVO₄ crystal was cooled by liquid nitrogen and end pumped by a 29.8-W fiber-coupled laser diode at 801 nm. A conversion efficiency of 41% and a slope efficiency of 46% were acquired with a continuous-wave output power of 12.2 W. An average power of 11.6 W was obtained at a pulse repetition frequency (PRF) of 10 kHz, corresponding to an optical-to-optical conversion efficiency of 38.9% and a slope efficiency of 41.4%. The energy per pulse of 1.8 mJ in 14 ns was achieved at 5 kHz with a peak power of 130 kW.