Background
Although tight blood pressure control is crucial in reducing vascular complications of diabetes, primary care providers often
fail to appropriately intensify antihypertensive medications.
Objective
To identify novel visit-based factors associated with intensification of antihypertensive medications in adults with diabetes.
Design
Non-concurrent prospective cohort study.
Patients
A total of 254 patients with type 2 diabetes and hypertension enrolled in an academically affiliated managed care program.
Over a 24-month interval (1999–2001), we identified 1,374 visits at which blood pressure was suboptimally controlled (systolic
BP ≥ 140 mmHg or diastolic BP ≥ 90 mmHg).
Measurements and Main Results
Intensification of antihypertensive medications at each visit was the primary outcome. Primary care providers intensified
antihypertensive treatment in only 176 (13%) of 1,374 visits at which blood pressure was elevated. As expected, higher mean
systolic and mean diastolic blood pressures were important predictors of intensification. Treatment was also more likely to
be intensified at visits that were “routine” odds ratio (OR) 2.08; 95% Confidence Interval [95% CI] 1.36–3.18), or that paired
patients with their usual primary care provider (OR 1.84; 95% CI 1.11–3.06). In contrast, several factors were associated
with failure to intensify treatment, including capillary glucose >150 mg/dL (OR 0.54; 95% CI 0.31–0.94) and the presence of
coronary heart disease (OR 0.61; 95% CI 0.38–0.95). Co-management by a cardiologist accounted partly for this failure (OR
0.65; 95% CI 0.41–1.03).
Conclusions
Failure to appropriately intensify antihypertensive treatment is common in diabetes care. Clinical distractions and shortcomings
in continuity and coordination of care are possible targets for improvement.
KEY WORDS diabetes mellitus - hypertension - health services - cohort study