Over the past 20 years, several nicotine replacement therapies (NRTs) have been approved for use as smoking cessation aids, with over-the-counter use of these products approved beginning in 1996. To date, only one econometric study has examined the impact of NRT on cigarette demand, providing limited evidence that the availability of these products has reduced cigarette demand. This paper adds to this limited literature by examining the impact of NRT availability, pricing, and use on U.S. cigarette demand, concluding that NRT is a substitute for cigarettes and that the elasticity of cigarette demand with respect to NRT sales is-0.06.