This paper presents how to manage Virtual Organizations to enable efficient collaboration and/or cooperation as a result of a flexible and parametrical model. The CAM (Collaborative/Cooperative Awareness Management) model promotes collaboration around resources-sharing infrastructures, endorsing interaction by means of a set of rules. This model focuses on responding to specific demanding circumstances at a given moment, while optimizes resources communication and behavioural agility to get a common goal: the establishment of collaborative dynamic virtual organizations. This paper also describes how CAM works in some specific examples and scenarios, and how the CAM Rules-Based Management Application (based on Web Services and named WS-CAM) has been designed and validated to encourage resources to be involved in collaborative performances, tackling efficiently demanding situations without hindering the own purposes of each of these resources.