This study examines correlates of sociopsychological post-migration depression in Pakistani Ismaili Muslim adolescent females residing in the United States using quantitative information obtained through a questionnaire. Analysis of the questionnaire included descriptive statistics, Pearson product moment correlation coefficients, and multiple regression to describe a final model of risk factors related to depression in these adolescents. Longer periods of stay in the United States, young age at migration, and speaking more English were associated with low sociopsychological stress scores. Adolescents who reported a longer period of stay in the United States and lower levels of sociopsychological stress were less likely to be depressed.