“Much as I dislike the idea of ages, I think a good case can be made that science has now moved from an Age of Reductionism to an Age of Emergence, a time when the search for ultimate causes of things shifts from the behavior of parts to the behavior of the collective” (Laughlin 2005, p. 208). This quotation by Nobel laureate in physics, Robert B. Laughlin, in his recent book, A Different Universe, raises interesting scientific and philosophical issues. Bench chemists continue successfully to synthesize new compounds and report results through quantitative and structural analyses of constitutive elements. The whole continues to be understood by analysis of the parts. The relatively recent science of emergence comes with a different perspective: how to explain novel, irreducible, and unpredictable appearances in cosmic evolution? New wholes seem to be more that the sum of their parts. How do these wholes come to exist? Do classical concepts of matter satisfy the science of emergence? Descriptions of nature’s phenomena that challenge classical interpretations of the “Age of Reductionism” are presented to stimulate possible new scientific and philosophical concepts for an age of reductionism and emergence.