A paleoseismological study of the medieval Kamenka fortress in the northern part of the Issyk-Kul Lake depression, northern Tien Shan in Kyrgyzstan, revealed an oblique slip thrust fault scarp offsetting the fortification walls. This 700 m long scarp is not related to the 1911 Kebin Earthquake (Ms 8.2) fault scarps which are widespread in the region. As analysis of stratigraphy in a paleoseismic trench and archaeological evidence reveal, it can be assigned to a major twelfth century a.d. earthquake which produced up to 4 m of oblique slip thrusting antithetic to that of the nearby dominant faults. The inferred surface rupturing earthquake apparently caused the fortress destruction and was likely the primary reason for its abandonment, not the Mongolian–Tatar invasions as previously thought.