PhyloGrid is a new tool continuously in progress whose aim is two-fold: to reduce the technological divide that a partial scientific community with low computational skills has for accessing new powerful computational platforms such as Grid; and, to develop a user-friendly interface by means of a workflow integrated in a web-portal. MrBayes software has been selected for calculating the evolutionary history of the species which is being integrated into new tools that performs the execution of jobs. Finally, this new application has been tested on the Human Papillomavirus.