The rate of evacuation of solid food from the stomach was investigated in chronic experiments on dogs with fistulas of the stomach and proximal part of the duodenum. After exclusion of the pyloric spincter (by the operations of pyloroplasty or gastroduodenostomy) the evacuatory function of the stomach remained basically compensated although, judging from the free passage of edible rubber balls 3 mm in diameter from the stomach into the duodenum, no structures replacing the pyloric sphincter could be found. Compensation of the evacuatory function of the stomach under these conditions is achieved through a marked increase in the role of the enterogastric reflex.
Key words pyloric sphincter - evacuation from the stomach - drainage operations
Department of Pharmacology and Experimental Pathology of the Digestive Tract, Research Institute of Physiology, Kiev University. (Presented by Academician of the Academy of Medical Sciences of the USSR V. S. Savel''ev.) Translated from Byulleten'' Éksperimental''noi Biologii i Meditsiny, Vol. 83, No. 6, pp. 666–669, June, 1977.