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Abstract

New alkyl carbonates of gamma-cyclodextrin have been obtained. These derivatives show lower haemolytic effect than the parent gamma-cyclodextrin. The complexation behaviour was tested with three important drugs, namely: progesterone, diazepam and flurbiprofen. DSC analyses were consistent with the inclusion complex formation.

diazepam - flurbiprofen - haemolysis - progesterone - solubilising agents

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