This article shows that the efficiency of state-space exploration techniques using decision diagrams can be drastically improved by exploiting the interleaving semantics underlying many event-based and component-based system models. A new algorithm for symbolically generating state spaces is presented that (i) encodes a model’s state vectors with Multi–valued Decision Diagrams (MDDs) rather than flattening them into BDDs and (ii) partitions the model’s Kronecker–consistent next–state function by event and subsystem, thus enabling multiple lightweight next–state transformations rather than a single heavyweight one. Together, this paves the way for a novel iteration order, called saturation, which replaces the breadth–first search order of traditional algorithms. The resulting saturation algorithm is implemented in the tool SMART, and experimental studies show that it is often several orders of magnitude better in terms of time efficiency, final memory consumption, and peak memory consumption than existing symbolic algorithms.